法医学中的免疫组织化学研究：小型综述

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详细

确定死因，正确且准确地确定机械损伤生前性质及其时效是现代法医学面临的最重要问题之一。

传统上，显微解剖学方法是研究组织的主要方法。随着时间的推移，增加了组织化学分析，扩大了诊断的可能性。因为免疫组织化学方法的进步，现代医学技术可以更深入地研究组织。这种基于组织结构特异性染色的创新方法在确定死亡原因、损伤生前性质和时效性方面发挥了重要作用，在信息量和准确性方面显着优于之前的方法。此外，该方法可以识别炎症反应的标志物，如细胞因子，以及与组织愈合相关的成分，如生长因子。这不仅有助于确认损伤生前情况，还有助于评估其愈合阶段，从而大大提高了确定受伤时间的准确性。在区分真实损伤和模拟创伤性损伤的死后变化时，使用免疫组织化学具有重要意义。因此，将该方法引入法医学实践中，有利于更客观、更准确的鉴定，最大限度地减少诊断错误的可能性。

免疫组织化学技术的进一步改进和所用标记物范围的扩大为法医学开辟了新的前景，提高了鉴定结论的可靠性和信息量。

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作者简介

Olga O. Frolova

Moscow Regional Research and Clinical Institute; Bureau of Forensic Medical Examination

Email: olga.frolog@yandex.ru
ORCID iD: 0000-0002-0785-6819
SPIN 代码: 5893-5925

MD

俄罗斯联邦, Moscow; Moscow

Aleksandr V. Maksimov

Moscow Regional Research and Clinical Institute; State University of Education

编辑信件的主要联系方式.
Email: mcsim2002@mail.ru
ORCID iD: 0000-0003-1936-4448
SPIN 代码: 3134-8457

MD, Dr. Sci. (Medicine), Assistant Professor

俄罗斯联邦, Moscow; 24 Vera Voloshina st, Mytishi,141014

Timofey S. Sokolov

State University of Education

Email: slantima@mail.ru
ORCID iD: 0009-0002-7659-0986
SPIN 代码: 8814-9942
俄罗斯联邦, 24 Vera Voloshina st, Mytishi,141014

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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