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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Forensic Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Forensic Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Судебная медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2411-8729</issn><issn publication-format="electronic">2409-4161</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">762</article-id><article-id pub-id-type="doi">10.17816/fm762</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Экспертная практика</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>临床病例报告</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Issues on forensic diagnostics for pyrethroid lambda-cyhalothrin poisoning</article-title><trans-title-group xml:lang="ru"><trans-title>К вопросу судебно-медицинской диагностики отравлений пиретроидом лямбда-цигалотрином</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>关于拟除虫菊酯（高效氯氟氰菊酯）中毒的法医学鉴定问题</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6520-9540</contrib-id><name-alternatives><name xml:lang="en"><surname>Chizhikova</surname><given-names>Inna O.</given-names></name><name xml:lang="ru"><surname>Чижикова</surname><given-names>Инна Олеговна</given-names></name><name xml:lang="zh"><surname>Chizhikova</surname><given-names>Inna O.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>inna.o.chizhikova@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2416-3627</contrib-id><name-alternatives><name xml:lang="en"><surname>Gornostaev</surname><given-names>Dmitry V.</given-names></name><name xml:lang="ru"><surname>Горностаев</surname><given-names>Дмитрий Викторович</given-names></name><name xml:lang="zh"><surname>Gornostaev</surname><given-names>Dmitry V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.)</p></bio><email>gornost@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2219-5315</contrib-id><name-alternatives><name xml:lang="en"><surname>Shigeev</surname><given-names>Sergey V.</given-names></name><name xml:lang="ru"><surname>Шигеев</surname><given-names>Сергей Владимирович</given-names></name><name xml:lang="zh"><surname>Shigeev</surname><given-names>Sergey V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Med.)</p></bio><email>shigeev@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Bureau of Forensic Medical Expertise</institution></aff><aff><institution xml:lang="ru">Бюро судебно-медицинской экспертизы</institution></aff><aff><institution xml:lang="zh">Bureau of Forensic Medical Expertise</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2023-08-02" publication-format="electronic"><day>02</day><month>08</month><year>2023</year></pub-date><pub-date date-type="pub" iso-8601-date="2023-10-19" publication-format="electronic"><day>19</day><month>10</month><year>2023</year></pub-date><volume>9</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>337</fpage><lpage>348</lpage><history><date date-type="received" iso-8601-date="2022-11-29"><day>29</day><month>11</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2023-06-28"><day>28</day><month>06</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><copyright-holder xml:lang="zh">Eco-Vector</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-10-19"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</ali:license_ref></license></permissions><self-uri xlink:href="https://for-medex.ru/jour/article/view/762">https://for-medex.ru/jour/article/view/762</self-uri><abstract xml:lang="en"><p>This is a case of poisoning with lambda-cyhalothrin, a synthetic pyrethroid, in a family of three (2 deaths). A postmortem examination revealed biochemical and micromorphological markers of lambda-cyhalothrin poisoning. In addition, an experimental model using laboratory animals (rats) was created to confirm the possibility of developing these lesions during the course of synthetic pyrethroid poisoning. Indeed, not only a similar clinical picture but also the same laboratory results were obtained.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлен случай отравления синтетическим пиретроидом лямбда-цигалотрином семьи из трёх человек с двумя смертельными исходами. При посмертном исследовании выявлены биохимические и микроморфологические маркеры отравления. Дополнительно создана экспериментальная модель на лабораторных животных (крысах) для подтверждения возможности развития указанных поражений в ходе течения отравления синтетическим пиретроидом, при этом в экспериментальной модели получены не только аналогичная клиническая картина, но и результаты лабораторных исследований.</p></trans-abstract><trans-abstract xml:lang="zh"><p>本文介绍一个三口之家合成拟除虫菊酯（高效氯氟氰菊酯）中毒的病例，其中两人死亡。尸检显示了生物化学和微观形态学的中毒标志。此外，还在实验动物（大鼠）身上建立了一个实验模型，以证实在合成拟除虫菊酯中毒过程中发生上述病变的可能性，同时，在实验模型中，不仅临床症状相似，实验室结果也相似。</p></trans-abstract><kwd-group xml:lang="en"><kwd>intoxication</kwd><kwd>poisoning</kwd><kwd>pyrethroids</kwd><kwd>lambda-cyhalothrin</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>интоксикация</kwd><kwd>отравление</kwd><kwd>пиретроиды</kwd><kwd>лямбда-цигалотрин</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>中毒</kwd><kwd>拟除虫菊酯</kwd><kwd>高效氯氟氰菊酯</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Fedorovtsev AL, Rеvnitskaya LA, Koroleva EI, Edelev NS. 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